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April 9th, 2025
Depo-Provera® is an injectable contraceptive that has been widely prescribed over the years for birth control and management of other medical conditions. But recent studies have demonstrated a correlation between extended use of Depo-Provera and an increased risk of developing a type of brain tumor typically known as a meningioma with one study showing a 5.6-fold increase in the risk of developing intracranial meningioma in women who used Depo-Provera for more than one year. A number of lawsuits have been and are being filed against Pfizer, the manufacturer of Depo-Provera, where plaintiffs allege that Pfizer failed to adequately warn users about the potential risks of taking the medication.
In fact, the number of impacted individuals has reached the point where The Judicial Panel on Multidistrict Litigation (JPML) has consolidated numerous federal cases into a multidistrict litigation (MDL) group to streamline pretrial proceedings. Judge Casey Rodgers has been appointed to oversee the Depo-Provera MDL in the Northern District of Florida. Judge Rodgers has extensive experience with MDL proceedings, having most recently handled the 3M Combat Earplug MDL. Like that action, the Depo-Provera consolidation aims to efficiently manage the growing number of lawsuits – estimated to range between 27,752 to 30,261 total cases within the 18-55 age demographic.
Meningiomas vary in type and these lawsuits involve all varieties for now. Those include:
World Health Organization Grade I (Benign) meningiomas (about 80-85% of all cases):
| Meningothelial (Syncytial) Meningioma | Microcystic Meningioma |
| Fibrous (Fibroblastic) Meningioma | Secretory Meningioma |
| Transitional (Mixed) Meningioma | Lymphoplasmacyte-rich Meningioma |
| Psammomatous Meningioma | Metaplastic Meningioma; |
| Angiomatous Meningioma |
World Health Organization Grade II meningiomas (about 15-20% of all cases):
Atypical Meningioma
Chordoid Meningioma
Clear Cell Meningioma
World Health Organization Grade III (Aggressive) meningiomas (about 1-3% of all cases):
Anaplastic (Malignant) Meningioma
Rhabdoid Meningioma
Papillary Meningioma
The Depo-Provera® lawsuit is actively underway and in the discovery phase. If you believe you or a loved one may have developed meningioma after using Depo-Provera® and would like to learn more about your legal rights, you should contact an experienced law firm right away to explore claim options.
